Cornea verticillata caused by Fabry diseaseCórnea verticilata por doença de Fabry

DOI: 10.1590/S1679-45082014AI2901 A 33-year-old woman who works as a yoga teacher and lived in the city of Rio de Janeiro (RJ) Brazil, sought ophthalmologic care at a routine examination. She did not report comorbidities and previous or regular use of medicines of any type. At examination the patient had good corrected visual acuity of 20/20 in both eyes. Biomicroscopy showed bilateral corneal verticillata, and in the rest of examination no other abnormalities were seen. Fabry disease is hereditary and X-chromosome linked. This disease is caused by deficiency of the enzyme α-galactosidase A that leads to progressive accumulation of lipid substances in the interior of the endothelium and smooth muscles of blood vessels so that affecting several organs.(1) Men are more affected by Fabry disease because they had the X chromosome Figure 1. Biomicroscopy showing the corneal verticillata